Miscarriage is a painful and, unfortunately, common event, occurring in a reported 20 percent of all pregnancies. Multiple miscarriages, defined as three or more successive losses, are both traumatic and a symptom of greater health risk, according to the experts at Repromedix, a specialty infertility testing lab in Massachusetts. Approximately 7 of every 1,000 women who become pregnant will experience multiple miscarriages, known medically as Recurrent Pregnancy Loss (RPL).

According to scientists at Repromedix, http://www.repromedix.com/, the pain of recurrent pregnancy loss may be compounded by its significance as a symptom of a serious medical condition with lifelong implications.

"Miscarriage patients who test positive for Thrombophilia (abnormally high blood clotting) may not only be at risk for more miscarriages but also for broader health problems such as stroke or pulmonary embolism," says Dr. Benjamin Rivnay, Repromedix' vice president for R&D.

* Thrombophilia may be a contributing factor in 40-60 percent of unexplained multiple miscarriages. Women with consecutive, unexplained pregnancy losses or a history of coagulation disorder and one or more miscarriage should be tested. Potential appropriate tests include Factor V Leiden (coagulation), Prothrombin Mutation, Antithrombin Activity and LAC (Lupus Anti-coagulant). * Autoimmune Diseases, such as lupus or thyroid conditions, are associated with RPL and infertility. Autoimmune disorders can affect many aspects of health, from the thyroid to the digestive system. If you have a history of autoimmune disease and unexplained RPL, ask about these potentially appropriate tests: ACA/APA, LAC (Lupus Anti-coagulant). * Endocrine Disorders, such as PCOS (Polycystic Ovarian Syndrome), correlate with a higher rate of miscarriage, gestational diabetes, and pregnancy-induced high blood pressure. Women with PCOS are also at higher risk for heart disease. Women with RPL and such physical symptoms as menstrual disorders, skin disorders, or high blood pressure should ask about specialty Glucose, Insulin, and Testosterone tests.

Diagnostic tests can help your OB/GYN uncover, treat and counsel for these and other conditions. Visit http://www.repromedix.com/ for more information about diagnostic tests and helpful links.

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EDITORS' ADVISORY: Dr. Rivnay is available for interviews. Published studies available to confirm information above.